The Effect of Mini-PEG-Based Spacer Length on Binding and Pharmacokinetic Properties of a (68)Ga-Labeled NOTA-Conjugated Antagonistic Analog of Bombesin

The overexpression of gastrin-releasing peptide receptor (GRPR) in cancer can be used for peptide-receptor mediated radionuclide imaging and therapy. We have previously shown that an antagonist analog of bombesin RM26 conjugated to 1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA...

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Detalles Bibliográficos
Autores principales: Varasteh, Zohreh, Rosenström, Ulrika, Velikyan, Irina, Mitran, Bogdan, Altai, Mohamed, Honarvar, Hadis, Rosestedt, Maria, Lindeberg, Gunnar, Sörensen, Jens, Larhed, Mats, Tolmachev, Vladimir, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270800/
https://www.ncbi.nlm.nih.gov/pubmed/25036155
http://dx.doi.org/10.3390/molecules190710455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270800/
https://www.ncbi.nlm.nih.gov/pubmed/25036155
http://dx.doi.org/10.3390/molecules190710455

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