3D-QSAR/CoMFA-Based Structure-Affinity/Selectivity Relationships of Aminoalkylindoles in the Cannabinoid CB1 and CB2 Receptors

A 3D-QSAR (CoMFA) study was performed in an extensive series of aminoalkylindoles derivatives with affinity for the cannabinoid receptors CB1 and CB2. The aim of the present work was to obtain structure-activity relationships of the aminoalkylindole family in order to explain the affinity and select...

Descripción completa

Detalles Bibliográficos
Autores principales: Mella-Raipán, Jaime, Hernández-Pino, Santiago, Morales-Verdejo, César, Pessoa-Mahana, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270810/
https://www.ncbi.nlm.nih.gov/pubmed/24603555
http://dx.doi.org/10.3390/molecules19032842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270810/
https://www.ncbi.nlm.nih.gov/pubmed/24603555
http://dx.doi.org/10.3390/molecules19032842

Ejemplares similares