ROS-Mediated Cytotoxic Effect of Copper(II) Hydrazone Complexes against Human Glioma Cells

2-Acetylpyridine acetylhydrazone (H2AcMe), 2-benzoylpyridine acetylhydrazone (H2BzMe) and complexes [Cu(H2AcMe)Cl(2)] (1) and [Cu(H2BzMe)Cl(2)] (2) were assayed for their cytotoxicity against wild type p53 U87 and mutant p53 T98 glioma cells, and against MRC-5 fibroblast cells. Compounds 1 and 2 pro...

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Detalles Bibliográficos
Autores principales: Despaigne, Angel A. Recio, Da Silva, Jeferson G., da Costa, Pryscila R., dos Santos, Raquel G., Beraldo, Heloisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270821/
https://www.ncbi.nlm.nih.gov/pubmed/25350363
http://dx.doi.org/10.3390/molecules191117202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270821/
https://www.ncbi.nlm.nih.gov/pubmed/25350363
http://dx.doi.org/10.3390/molecules191117202

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