Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

Previously designed cyclic peptide antagonist c[YYDEGLEE]-NH(2) disrupts the interaction between vascular endothelial growth factor (VEGF) and its receptors (VEGFRs). It represents a promising tool in the fight against cancer and age-related macular degeneration. We described in this paper the optim...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Gagey-Eilstein, Nathalie, Broussy, Sylvain, Reille-Seroussi, Marie, Huguenot, Florent, Vidal, Michel, Liu, Wang-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270838/
https://www.ncbi.nlm.nih.gov/pubmed/25264829
http://dx.doi.org/10.3390/molecules191015391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270838/
https://www.ncbi.nlm.nih.gov/pubmed/25264829
http://dx.doi.org/10.3390/molecules191015391

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