Rational Design and Synthesis of Altered Peptide Ligands based on Human Myelin Oligodendrocyte Glycoprotein 35–55 Epitope: Inhibition of Chronic Experimental Autoimmune Encephalomyelitis in Mice

Experimental autoimmune encephalomyelitis (EAE) is a demyelinating disease of the central nervous system and is an animal model of multiple sclerosis (MS). Although the etiology of MS remains unclear, there is evidence T-cell recognition of immunodominant epitopes of myelin proteins, such as the 35–...

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Detalles Bibliográficos
Autores principales: Tselios, Theodore, Aggelidakis, Mihalis, Tapeinou, Anthi, Tseveleki, Vivian, Kanistras, Ioannis, Gatos, Dimitrios, Matsoukas, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270842/
https://www.ncbi.nlm.nih.gov/pubmed/25375337
http://dx.doi.org/10.3390/molecules191117968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270842/
https://www.ncbi.nlm.nih.gov/pubmed/25375337
http://dx.doi.org/10.3390/molecules191117968

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