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Identification of Two Novel α(1)-AR Agonists Using a High-Throughput Screening Model
α(1)-Adrenoceptors (ARs; 1A, 1B, and 1D) have been determined to perform different prominent functions in the physiological responses of the sympathetic nervous system. A high-throughput screening assay (HTS) was set up to detect α(1)-AR subtype-selective agonists by a dual-luciferase reporter assay...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270864/ https://www.ncbi.nlm.nih.gov/pubmed/25140448 http://dx.doi.org/10.3390/molecules190812699 |