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Identification of Two Novel α(1)-AR Agonists Using a High-Throughput Screening Model

α(1)-Adrenoceptors (ARs; 1A, 1B, and 1D) have been determined to perform different prominent functions in the physiological responses of the sympathetic nervous system. A high-throughput screening assay (HTS) was set up to detect α(1)-AR subtype-selective agonists by a dual-luciferase reporter assay...

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Detalles Bibliográficos
Autores principales: Xu, Fang, Chen, Hong, He, Xuelan, Xu, Jingyi, Xu, Bingbing, Huang, Biyun, Liang, Xue, Yuan, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270864/
https://www.ncbi.nlm.nih.gov/pubmed/25140448
http://dx.doi.org/10.3390/molecules190812699