Nilotinib Enhances the Efficacy of Conventional Chemotherapeutic Drugs in CD34(+)CD38(−) Stem Cells and ABC Transporter Overexpressing Leukemia Cells

Incomplete chemotherapeutic eradication of leukemic CD34(+)CD38(−) stem cells is likely to result in disease relapse. The purpose of this study was to evaluate the effect of nilotinib on eradicating leukemia stem cells and enhancing the efficacy of chemotherapeutic agents. Our results showed that AB...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Wang, Xiao-Kun, Shi, Cheng-Jun, Zhang, Hui, Hu, Ya-Peng, Chen, Yi-Fan, Fu, Li-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270868/
https://www.ncbi.nlm.nih.gov/pubmed/24651611
http://dx.doi.org/10.3390/molecules19033356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270868/
https://www.ncbi.nlm.nih.gov/pubmed/24651611
http://dx.doi.org/10.3390/molecules19033356

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