Asymmetric Synthesis of 4,1-Benzoxazepine-2,5-Diones — Effect of the Halogen of (2S)-α-Haloacids

Novel chiral 4,1-benzoxazepine-2,5-diones have been unusually synthesized in a single step by exploiting the chiral pool methodology. Substituted anthranilic acids afford N-acylanthranilic acids and (3R)-3-alkyl-4,1-benzoxazepines-2,5-dione upon coupling with α-chloroacids or α-bromoacids, respectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Rubab, Syeda Laila, Nisar, Bushra, Raza, Abdul Rauf, Ullah, Nisar, Tahir, Muhammad Nawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270870/
https://www.ncbi.nlm.nih.gov/pubmed/24366090
http://dx.doi.org/10.3390/molecules19010139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270870/
https://www.ncbi.nlm.nih.gov/pubmed/24366090
http://dx.doi.org/10.3390/molecules19010139

Ejemplares similares