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Penostatin Derivatives, a Novel Kind of Protein Phosphatase 1B Inhibitors Isolated from Solid Cultures of the Entomogenous Fungus Isaria tenuipes

Protein tyrosine phosphatase 1B (PTP1B) is implicated as a negative regulator of insulin receptor (IR) signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes. Therefore, small molecular inhibitors of PTP1B can be considered as an attracti...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Peng, Yang, Chun-Gui, Wei, Pei-Yao, Li, Lin, Luo, Du-Qiang, Zheng, Zhi-Hui, Lu, Xin-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270892/
https://www.ncbi.nlm.nih.gov/pubmed/24481115
http://dx.doi.org/10.3390/molecules19021663