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Synthetic Genistein Glycosides Inhibiting EGFR Phosphorylation Enhance the Effect of Radiation in HCT 116 Colon Cancer Cells

The need to find new EGFR inhibitors for use in combination with radiotherapy in the treatment of solid tumors has drawn our attention to compounds derived from genistein, a natural isoflavonoid. The antiproliferative potential of synthetic genistein derivatives used alone or in combination with ion...

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Detalles Bibliográficos
Autores principales: Gruca, Aleksandra, Krawczyk, Zdzisław, Szeja, Wiesław, Grynkiewicz, Grzegorz, Rusin, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270897/
https://www.ncbi.nlm.nih.gov/pubmed/25401399
http://dx.doi.org/10.3390/molecules191118558