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Study on the Cytotoxic Activity of Drimane Sesquiterpenes and Nordrimane Compounds against Cancer Cell Lines

Twelve drimanes, including polygodial (1), isopolygodial (2), drimenol (3), confertifolin (4), and isodrimenin (5), were obtained from natural sources. Semi-synthetic derivatives 6–12 were obtained from 1 and 2, and cytotoxic activity was evaluated in vitro against cancer cell lines (HT-29, MDA-MB23...

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Detalles Bibliográficos
Autores principales: Montenegro, Ivan, Tomasoni, Giacomo, Bosio, Claudia, Quiñones, Natalia, Madrid, Alejandro, Carrasco, Hector, Olea, Andres, Martinez, Rolando, Cuellar, Mauricio, Villena, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270921/
https://www.ncbi.nlm.nih.gov/pubmed/25412045
http://dx.doi.org/10.3390/molecules191118993