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Microsomal Prostaglandin E Synthase-1 Deficiency Exacerbates Pulmonary Fibrosis Induced by Bleomycin in Mice

Microsomal prostaglandin E2 synthase-1 (mPGES-1), an inducible enzyme that converts prostaglandin H2 (PGH(2)) to prostaglandin E2 (PGE(2)), plays an important role in a variety of diseases. So far, the role of mPGES-1 in idiopathic pulmonary fibrosis (IPF) remained unknown. The current study aimed t...

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Detalles Bibliográficos
Autores principales: Wei, Bo, Cai, Linhong, Sun, Dan, Wang, Yanhua, Wang, Cairui, Chai, Xiaoyu, Xie, Feng, Su, Ming, Ding, Fangrui, Liu, Jie, Yang, Jichun, Guan, Youfei, Liu, Xinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270927/
https://www.ncbi.nlm.nih.gov/pubmed/24756129
http://dx.doi.org/10.3390/molecules19044967