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Design, Synthesis and the Biological Evaluation of New 1,3-Thiazolidine-4-ones Based on the 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one Scaffold

New thiazolidine-4-one derivatives based on the 4-aminophenazone (4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) scaffold have been synthesized as potential anti-inflammatory drugs. The pyrazoline derivatives are known especially for their antipyretic, analgesic and anti-inflammatory effects, but...

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Detalles Bibliográficos
Autores principales: Apotrosoaei, Maria, Vasincu, Ioana Mirela, Dragan, Maria, Buron, Frédéric, Routier, Sylvain, Profire, Lenuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270961/
https://www.ncbi.nlm.nih.gov/pubmed/25255761
http://dx.doi.org/10.3390/molecules190913824