Design and Synthesis of Thiazolo[5,4-f]quinazolines as DYRK1A Inhibitors, Part I

The convenient synthesis of a library of novel 6,6,5-tricyclic thiazolo[5,4-f] quinazolines (forty molecules) was achieved mainly under microwave irradiation. Dimroth rearrangement and 4,5-dichloro-1,2,3,-dithiazolium chloride (Appel salt) chemistry were associated for the synthesis of a novel 6-ami...

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Detalles Bibliográficos
Autores principales: Foucourt, Alicia, Hédou, Damien, Dubouilh-Benard, Carole, Désiré, Laurent, Casagrande, Anne-Sophie, Leblond, Bertrand, Loäec, Nadège, Meijer, Laurent, Besson, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270991/
https://www.ncbi.nlm.nih.gov/pubmed/25268714
http://dx.doi.org/10.3390/molecules191015546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270991/
https://www.ncbi.nlm.nih.gov/pubmed/25268714
http://dx.doi.org/10.3390/molecules191015546

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