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Synthesis, Crystal Structure, and Biological Evaluation of a Series of Phloretin Derivatives

A one-step synthesis of phloretin derivatives 2–11 from phloretin in good to excellent yields is reported. Their structures were characterized by (1)H-NMR, (13)C-NMR and MS, and the structures of 8 and 11 were determined by X-ray diffraction analysis. A mechanism for the formation of 9–11 is propose...

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Detalles Bibliográficos
Autores principales: Wang, Li, Li, Zheng-Wei, Zhang, Wei, Xu, Rui, Gao, Fei, Liu, Yang-Feng, Li, Ya-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271035/
https://www.ncbi.nlm.nih.gov/pubmed/25314605
http://dx.doi.org/10.3390/molecules191016447