EOP, a Newly Synthesized Ethyl Pyruvate Derivative, Attenuates the Production of Inflammatory Mediators via p38, ERK and NF-κB Pathways in Lipopolysaccharide-Activated BV-2 Microglial Cells

Microglia-induced neuroinflammation is an important pathological mechanism influencing various neurodegenerative disorders. Excess activation of microglia produces a myriad of proinflammatory mediators that decimate neurons. Hence, therapeutic strategies aimed to suppress the activation of microglia...

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Detalles Bibliográficos
Autores principales: Min, Soon, More, Sandeep Vasant, Park, Ju-Young, Jeon, Sae-Bom, Park, Shin Young, Park, Eun-Jung, Yoon, Sung-Hwa, Choi, Dong-Kug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271075/
https://www.ncbi.nlm.nih.gov/pubmed/25429561
http://dx.doi.org/10.3390/molecules191219361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271075/
https://www.ncbi.nlm.nih.gov/pubmed/25429561
http://dx.doi.org/10.3390/molecules191219361

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