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Self-Assembled Micelles Composed of Doxorubicin Conjugated Y-Shaped PEG-Poly(glutamic acid)(2) Copolymers via Hydrazone Linkers

In this work, micelles composed of doxorubicin-conjugated Y-shaped copolymers (YMs) linked via an acid-labile linker were constructed. Y-shaped copolymers of mPEG-b-poly(glutamate-hydrazone-doxorubicin)(2) and linear copolymers of mPEG-b-poly(glutamate-hydrazone-doxorubicin) were synthesized and cha...

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Detalles Bibliográficos
Autores principales: Sui, Bowen, Xu, Hui, Jin, Jian, Gou, Jingxin, Liu, Jingshuo, Tang, Xing, Zhang, Yu, Xu, Jinghua, Zhang, Hongfeng, Jin, Xiangqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271086/
https://www.ncbi.nlm.nih.gov/pubmed/25116804
http://dx.doi.org/10.3390/molecules190811915