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Quantification of the Resveratrol Analogs trans-2,3-Dimethoxy-stilbene and trans-3,4-Dimethoxystilbene in Rat Plasma: Application to Pre-Clinical Pharmacokinetic Studies

trans-2,3-Dimethoxystilbene (2,3-DMS) and trans-3,4-dimethoxystilbene (3,4-DMS) are two synthetic resveratrol (trans-3,5,4'-trihydroxystilbene) analogs. In this study, a simple HPLC method was developed and validated to determine 2,3-DMS and 3,4-DMS in rat plasma. Chromatographic separation was...

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Detalles Bibliográficos
Autores principales: Ng, Shermain Yali, Cardullo, Nunzio, Yeo, Samuel Chao Ming, Spatafora, Carmela, Tringali, Corrado, Ong, Pei-Shi, Lin, Hai-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271088/
https://www.ncbi.nlm.nih.gov/pubmed/25004068
http://dx.doi.org/10.3390/molecules19079577