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Combined Dynamic Light Scattering and Raman Spectroscopy Approach for Characterizing the Aggregation of Therapeutic Proteins

Determination of the physicochemical properties of protein therapeutics and their aggregates is critical for developing formulations that enhance product efficacy, stability, safety and manufacturability. Analytical challenges are compounded for materials: (1) that are formulated at high concentrati...

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Detalles Bibliográficos
Autores principales: Lewis, E. Neil, Qi, Wei, Kidder, Linda H., Amin, Samiul, Kenyon, Stacy M., Blake, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271152/
https://www.ncbi.nlm.nih.gov/pubmed/25514228
http://dx.doi.org/10.3390/molecules191220888