Up-Regulation of Urotensin II and Its Receptor Contributes to Human Hepatocellular Carcinoma Growth via Activation of the PKC, ERK1/2, and p38 MAPK Signaling Pathways

Urotensin II (UII) and its receptor (UTR) have mitogenic effects on tumor growth. Our previous study demonstrated that the UII/UTR system is up-regulated in dithyinitrosamine-induced precancerous rat liver lesions. However, its role in human hepatocellular carcinoma remains unknown. In this study, t...

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Detalles Bibliográficos
Autores principales: Yu, Xiao-Tong, Wang, Peng-Yan, Shi, Zheng-Ming, Dong, Kun, Feng, Ping, Wang, Hong-Xia, Wang, Xue-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271171/
https://www.ncbi.nlm.nih.gov/pubmed/25514221
http://dx.doi.org/10.3390/molecules191220768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271171/
https://www.ncbi.nlm.nih.gov/pubmed/25514221
http://dx.doi.org/10.3390/molecules191220768

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