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Up-Regulation of Urotensin II and Its Receptor Contributes to Human Hepatocellular Carcinoma Growth via Activation of the PKC, ERK1/2, and p38 MAPK Signaling Pathways
Urotensin II (UII) and its receptor (UTR) have mitogenic effects on tumor growth. Our previous study demonstrated that the UII/UTR system is up-regulated in dithyinitrosamine-induced precancerous rat liver lesions. However, its role in human hepatocellular carcinoma remains unknown. In this study, t...
Autores principales: | Yu, Xiao-Tong, Wang, Peng-Yan, Shi, Zheng-Ming, Dong, Kun, Feng, Ping, Wang, Hong-Xia, Wang, Xue-Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271171/ https://www.ncbi.nlm.nih.gov/pubmed/25514221 http://dx.doi.org/10.3390/molecules191220768 |
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