Cargando…

Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro

Osteosarcoma is the most common malignant primary bone tumor in children and young adults and lung metastasis is the main cause of death in those patients. Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to exhibit cytotoxic effects, including antiproliferative and anti...

Descripción completa

Detalles Bibliográficos
Autores principales: Shang, Hung-Sheng, Chang, Jin-Biou, Lin, Ju-Hwa, Lin, Jing-Pin, Hsu, Shu-Chun, Liu, Chi-Ming, Liu, Jia-You, Wu, Ping-Ping, Lu, Hsu-Feng, Au, Man-Kuan, Chung, Jing-Gung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271177/
https://www.ncbi.nlm.nih.gov/pubmed/25322282
http://dx.doi.org/10.3390/molecules191016588