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Deguelin Inhibits the Migration and Invasion of U-2 OS Human Osteosarcoma Cells via the Inhibition of Matrix Metalloproteinase-2/-9 in Vitro
Osteosarcoma is the most common malignant primary bone tumor in children and young adults and lung metastasis is the main cause of death in those patients. Deguelin, a naturally occurring rotenoid, is known to be an Akt inhibitor and to exhibit cytotoxic effects, including antiproliferative and anti...
Autores principales: | Shang, Hung-Sheng, Chang, Jin-Biou, Lin, Ju-Hwa, Lin, Jing-Pin, Hsu, Shu-Chun, Liu, Chi-Ming, Liu, Jia-You, Wu, Ping-Ping, Lu, Hsu-Feng, Au, Man-Kuan, Chung, Jing-Gung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271177/ https://www.ncbi.nlm.nih.gov/pubmed/25322282 http://dx.doi.org/10.3390/molecules191016588 |
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