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EPR Spectroscopy of a Clinically Active (1:2) Copper(II)-Histidine Complex Used in the Treatment of Menkes Disease: A Fourier Transform Analysis of a Fluid CW-EPR Spectrum

Redox active transition metal ions (e.g., iron and copper) have been implicated in the etiology of many oxidative stress-related diseases including also neurodegenerative disorders. Unbound copper can catalyze formation of reactive oxygen species (hydroxyl radicals) via Fenton reaction/Haber–Weiss c...

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Detalles Bibliográficos
Autores principales: Gala, Lukas, Lawson, Michael, Jomova, Klaudia, Zelenicky, Lubomir, Congradyova, Andrea, Mazur, Milan, Valko, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271212/
https://www.ncbi.nlm.nih.gov/pubmed/24434671
http://dx.doi.org/10.3390/molecules19010980