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Pharmacological Importance of Optically Active Tetrahydro-β-carbolines and Synthetic Approaches to Create the C1 Stereocenter

1,2,3,4-Tetrahydro-β-carbolines (THβCs) are a pharmacologically important group of compounds belonging to the indole alkaloids. C1-Substituted optically active THβCs have been the target of extensive synthetic efforts due to the presence of the scaffold in numerous natural products and synthetic tar...

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Detalles Bibliográficos
Autores principales: Laine, Aino E., Lood, Christopher, Koskinen, Ari M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271216/
https://www.ncbi.nlm.nih.gov/pubmed/24473212
http://dx.doi.org/10.3390/molecules19021544