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Biopharmaceutical Profiling of New Antitumor Pyrazole Derivatives

Several new pyrazole derivatives have demonstrated promising antiproliferative and cytotoxic effects, but their poor solubility raised concerns over possible biopharmaceutical limitations. In order to improve their pharmaceutical potential we performed the biopharmaceutical profiling for nine pyrazo...

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Detalles Bibliográficos
Autores principales: Anuta, Valentina, Nitulescu, George Mihai, Dinu-Pîrvu, Cristina Elena, Olaru, Octavian Tudorel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271227/
https://www.ncbi.nlm.nih.gov/pubmed/25314601
http://dx.doi.org/10.3390/molecules191016381