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Spectroscopic and Molecular Docking Studies of the in Vitro Interaction between Puerarin and Cytochrome P450

Puerarin, an isoflavone glycoside extracted from Pueraria plants, has various medical functions. Cytochrome P450s (CYPs) are crucial phase I metabolizing enzymes, which have been spotlighted for their effects on drug metabolism. The interaction between puerarin and CYPs (CYP1A2 and CYP2D6) was inves...

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Detalles Bibliográficos
Autores principales: Shao, Jiangjuan, Chen, Jianwei, Li, Tingting, Zhao, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271238/
https://www.ncbi.nlm.nih.gov/pubmed/24743933
http://dx.doi.org/10.3390/molecules19044760