A Multi-Scale Computational Study on the Mechanism of Streptococcus pneumoniae Nicotinamidase (SpNic)

Nicotinamidase (Nic) is a key zinc-dependent enzyme in NAD metabolism that catalyzes the hydrolysis of nicotinamide to give nicotinic acid. A multi-scale computational approach has been used to investigate the catalytic mechanism, substrate binding and roles of active site residues of Nic from Strep...

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Detalles Bibliográficos
Autores principales: Ion, Bogdan F., Kazim, Erum, Gauld, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271260/
https://www.ncbi.nlm.nih.gov/pubmed/25268724
http://dx.doi.org/10.3390/molecules191015735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271260/
https://www.ncbi.nlm.nih.gov/pubmed/25268724
http://dx.doi.org/10.3390/molecules191015735

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