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Pharmacophore Generation from a Drug-like Core Molecule Surrounded by a Library Peptide via the 10BASE(d)-T on Bacteriophage T7
We have achieved site-specific conjugation of several haloacetamide derivatives into designated cysteines on bacteriophage T7-displayed peptides, which are fused to T7 capsid protein gp10. This easiest gp10 based-thioetherification (10BASE(d)-T) undergoes almost quantitatively like a click reaction...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271298/ https://www.ncbi.nlm.nih.gov/pubmed/24566316 http://dx.doi.org/10.3390/molecules19022481 |