Synthesis of Novel 2-(Substituted amino)alkylthiopyrimidin-4(3H)-ones as Potential Antimicrobial Agents

5-Alkyl-6-(substituted benzyl)-2-thiouracils 3a,c were reacted with (2-chloroethyl) diethylamine hydrochloride to afford the corresponding 2-(2-diethylamino)ethylthiopyrimidin-4(3H)-ones 4a,b. Reaction of 3a–c with N-(2-chloroethyl)pyrrolidine hydrochloride and/or N-(2-chloroethyl)piperidine hydroch...

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Detalles Bibliográficos
Autores principales: Attia, Mohamed I., El-Emam, Ali A., Al-Turkistani, Abdulghafoor A., Kansoh, Amany L., El-Brollosy, Nasser R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271362/
https://www.ncbi.nlm.nih.gov/pubmed/24378967
http://dx.doi.org/10.3390/molecules19010279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271362/
https://www.ncbi.nlm.nih.gov/pubmed/24378967
http://dx.doi.org/10.3390/molecules19010279

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