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Development of a Supercritical Fluid Chromatography-Tandem Mass Spectrometry Method for the Determination of Azacitidine in Rat Plasma and Its Application to a Bioavailability Study

Azacitidine is widely used for the treatment of myelodysplastic syndromes (MDS) and acute myelogenous leukaemia (AML). The analysis of azacitidine in biological samples is subject to interference by endogenous compounds. Previously reported high-performance liquid chromatography/tandem mass spectrom...

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Detalles Bibliográficos
Autores principales: Li, Dongpo, Zhang, Tianhong, Kou, Longfa, Zhang, Youxi, Sun, Jin, He, Zhonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271376/
https://www.ncbi.nlm.nih.gov/pubmed/24378972
http://dx.doi.org/10.3390/molecules19010342