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Pharmacological and Structure-Activity Relationship Evaluation of 4-aryl-1-Diphenylacetyl(thio)semicarbazides

This article describes the synthesis of six 4-aryl-(thio)semicarbazides (series a and b) linked with diphenylacetyl moiety along with their pharmacological evaluation on the central nervous system in mice and computational studies, including conformational analysis and electrostatic properties. All...

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Detalles Bibliográficos
Autores principales: Wujec, Monika, Kędzierska, Ewa, Kuśmierz, Edyta, Plech, Tomasz, Wróbel, Andrzej, Paneth, Agata, Orzelska, Jolanta, Fidecka, Sylwia, Paneth, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271380/
https://www.ncbi.nlm.nih.gov/pubmed/24743932
http://dx.doi.org/10.3390/molecules19044745