Synthesis and Biological Evaluation of New Pyridone-Annelated Isoindigos as Anti-Proliferative Agents

A selected set of substituted pyridone-annelated isoindigos 3a–f has been synthesized via interaction of 5- and 6-substituted oxindoles 2a–f with 6-ethyl-1,2,9-trioxopyrrolo[3,2-f]quinoline-8-carboxylic acid (1) in acetic acid at reflux. Among these isoindigos, the 5'-chloro and 5'-bromo d...

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Detalles Bibliográficos
Autores principales: Saleh, Ayman M., Al-As’ad, Randa M., El-Abadelah, Mustafa M., Sabri, Salim S., Zahra, Jalal A., Alaskar, Ahmed S., Aljada, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271423/
https://www.ncbi.nlm.nih.gov/pubmed/25157470
http://dx.doi.org/10.3390/molecules190913076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271423/
https://www.ncbi.nlm.nih.gov/pubmed/25157470
http://dx.doi.org/10.3390/molecules190913076

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