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Calculating Distortions of Short DNA Duplexes with Base Pairing Between an Oxidatively Damaged Guanine and a Guanine

DNA is constantly being oxidized, and oxidized DNA is prone to mutation; moreover, guanine is highly sensitive to several oxidative stressors. Several oxidatively damaged forms of guanine—including 2,2,4-triamino-5(2H)-oxazolone (Oz), iminoallantoin (Ia), and spiroiminodihydantoin (Sp)—can be paired...

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Detalles Bibliográficos
Autores principales: Suzuki, Masayo, Kino, Katsuhito, Morikawa, Masayuki, Kobayashi, Takanobu, Miyazawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271426/
https://www.ncbi.nlm.nih.gov/pubmed/25072203
http://dx.doi.org/10.3390/molecules190811030