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Mixture-Based Combinatorial Libraries from Small Individual Peptide Libraries: A Case Study on α(1)-Antitrypsin Deficiency

The design, synthesis and screening of diversity-oriented peptide libraries using a “libraries from libraries” strategy for the development of inhibitors of α(1)-antitrypsin deficiency are described. The major buttress of the biochemical approach presented here is the use of well-established solid-p...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Pin, Chu, Yen-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271437/
https://www.ncbi.nlm.nih.gov/pubmed/24840902
http://dx.doi.org/10.3390/molecules19056330