Novel Polycarbo-Substituted Alkyl (Thieno[3,2-c]quinoline)-2-Carboxylates: Synthesis and Cytotoxicity Studies

Direct one-pot base-promoted conjugate addition–elimination of 6,8-dibromo-4-chloroquinoline-3-carbaldehyde with methyl mercaptoacetate and subsequent cyclization afforded methyl [(6,8-dibromothieno[3,2-c]quinoline)]-2-carboxylate. The latter undergoes Suzuki-Miyaura cross-coupling with arylboronic...

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Detalles Bibliográficos
Autores principales: Mphahlele, Malose Jack, Maluleka, Marole Maria, Makhafola, Tshepiso Jan, Mabeta, Peace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271451/
https://www.ncbi.nlm.nih.gov/pubmed/25401397
http://dx.doi.org/10.3390/molecules191118527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271451/
https://www.ncbi.nlm.nih.gov/pubmed/25401397
http://dx.doi.org/10.3390/molecules191118527

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