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pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy

Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from very low to very high pH values. We compared avi...

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Detalles Bibliográficos
Autores principales: Köhler, Melanie, Karner, Andreas, Leitner, Michael, Hytönen, Vesa P., Kulomaa, Markku, Hinterdorfer, Peter, Ebner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271454/
https://www.ncbi.nlm.nih.gov/pubmed/25153869
http://dx.doi.org/10.3390/molecules190812531