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pH-Dependent Deformations of the Energy Landscape of Avidin-like Proteins Investigated by Single Molecule Force Spectroscopy
Avidin and avidin-like proteins are widely used in numerous techniques since the avidin-biotin interaction is known to be very robust and reliable. Within this study, we investigated this bond at the molecular level under harsh conditions ranging from very low to very high pH values. We compared avi...
Autores principales: | Köhler, Melanie, Karner, Andreas, Leitner, Michael, Hytönen, Vesa P., Kulomaa, Markku, Hinterdorfer, Peter, Ebner, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271454/ https://www.ncbi.nlm.nih.gov/pubmed/25153869 http://dx.doi.org/10.3390/molecules190812531 |
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