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Synthesis and Biological Evaluation of New Pleuromutilin Derivatives as Antibacterial Agents

Several pleuromutilin derivatives possessing thiadiazole moieties were synthesized via acylation reactions under mild conditions. The in vitro antibacterial activities of the derivatives against methicillin-resistant S. aureus, methicillin-resistant S. epidermidis, S. aureus, S. epidermidis, E. coli...

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Detalles Bibliográficos
Autores principales: Shang, Ruo-Feng, Wang, Guan-Hua, Xu, Xi-Ming, Liu, Si-Jie, Zhang, Chao, Yi, Yun-Peng, Liang, Jian-Ping, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271455/
https://www.ncbi.nlm.nih.gov/pubmed/25415471
http://dx.doi.org/10.3390/molecules191119050