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Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives
A new series of oxime ethers 4a–z was designed and synthesized to test the blocking activity against β(1) and β(2)-adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β(1) and β(2)-adrenergic receptors showed MolDock scores comparable to t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271474/ https://www.ncbi.nlm.nih.gov/pubmed/24658567 http://dx.doi.org/10.3390/molecules19033417 |