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Synthesis, Docking Study and β-Adrenoceptor Activity of Some New Oxime Ether Derivatives

A new series of oxime ethers 4a–z was designed and synthesized to test the blocking activity against β(1) and β(2)-adrenergic receptors. Docking of these ether derivatives into the active site of the identified 3D structures of β(1) and β(2)-adrenergic receptors showed MolDock scores comparable to t...

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Detalles Bibliográficos
Autores principales: Ghabbour, Hazem A., El-Bendary, Eman R., El-Ashmawy, Mahmoud B., El-Kerdawy, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271474/
https://www.ncbi.nlm.nih.gov/pubmed/24658567
http://dx.doi.org/10.3390/molecules19033417