TOMBU and COMBU as Novel Uronium-Type Peptide Coupling Reagents Derived from Oxyma-B

Here we describe two novel uronium salts, TOMBU and COMBU, derived from the recently described Oxyma-B for use in peptide bond synthesis. These coupling reagents are more stable than COMU in DMF. Furthermore, using various peptide synthetic models in solution and solid-phase synthesis, we reveal tha...

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Detalles Bibliográficos
Autores principales: Jad, Yahya E., Khattab, Sherine N., de la Torre, Beatriz G., Govender, Thavendran, Kruger, Hendrik G., El-Faham, Ayman, Albericio, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271478/
https://www.ncbi.nlm.nih.gov/pubmed/25412042
http://dx.doi.org/10.3390/molecules191118953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271478/
https://www.ncbi.nlm.nih.gov/pubmed/25412042
http://dx.doi.org/10.3390/molecules191118953

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