Design and Synthesis of Chalcone Derivatives as Inhibitors of the Ferredoxin — Ferredoxin-NADP(+) Reductase Interaction of Plasmodium falciparum: Pursuing New Antimalarial Agents

Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP(+) reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 1...

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Detalles Bibliográficos
Autores principales: Suwito, Hery, Jumina, Mustofa, Pudjiastuti, Pratiwi, Fanani, Much Zaenal, Kimata-Ariga, Yoko, Katahira, Ritsuko, Kawakami, Toru, Fujiwara, Toshimichi, Hase, Toshiharu, Mohd Sirat, Hasnah, Puspaningsih, Ni Nyoman Tri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271513/
https://www.ncbi.nlm.nih.gov/pubmed/25532844
http://dx.doi.org/10.3390/molecules191221473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271513/
https://www.ncbi.nlm.nih.gov/pubmed/25532844
http://dx.doi.org/10.3390/molecules191221473

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