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Design and Synthesis of Chalcone Derivatives as Inhibitors of the Ferredoxin — Ferredoxin-NADP(+) Reductase Interaction of Plasmodium falciparum: Pursuing New Antimalarial Agents

Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP(+) reductase interaction to pursue a new selective antimalaria agent. The synthesized compounds exhibited inhibition interactions between PfFd-PfFNR in the range of 1...

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Detalles Bibliográficos
Autores principales:	Suwito, Hery, Jumina, Mustofa, Pudjiastuti, Pratiwi, Fanani, Much Zaenal, Kimata-Ariga, Yoko, Katahira, Ritsuko, Kawakami, Toru, Fujiwara, Toshimichi, Hase, Toshiharu, Mohd Sirat, Hasnah, Puspaningsih, Ni Nyoman Tri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271513/ https://www.ncbi.nlm.nih.gov/pubmed/25532844 http://dx.doi.org/10.3390/molecules191221473

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