Studies on the Anticonvulsant Activity and Influence on GABA-ergic Neurotransmission of 1,2,4-Triazole-3-thione-Based Compounds

The anticonvulsant activity of several 1,2,4-triazole-3-thione derivatives on mouse maximal electroshock-induced seizures was tested in this study. Characteristic features of all active compounds were rapid onset of action and long lasting effect. Structure-activity observations showed that the prob...

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Detalles Bibliográficos
Autores principales: Plech, Tomasz, Kaproń, Barbara, Łuszczki, Jarogniew J., Wujec, Monika, Paneth, Agata, Siwek, Agata, Kołaczkowski, Marcin, Żołnierek, Maria, Nowak, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271529/
https://www.ncbi.nlm.nih.gov/pubmed/25090118
http://dx.doi.org/10.3390/molecules190811279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271529/
https://www.ncbi.nlm.nih.gov/pubmed/25090118
http://dx.doi.org/10.3390/molecules190811279

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