Celastrol Induces Apoptosis in Gefitinib-Resistant Non-Small Cell Lung Cancer Cells via Caspases-Dependent Pathways and Hsp90 Client Protein Degradation

Celastrol, a triterpene extracted from the Chinese herb Tripterygium wilfordii, has been shown to have multiple bioactivities. Although among these activities, its anti-cancer effects have attracted the most attention, the effect of celastrol on gefitinib-resistant non-small cell lung cancer (NSCLC)...

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Detalles Bibliográficos
Autores principales: Fan, Xing-Xing, Li, Na, Wu, Jian-Lin, Zhou, Yan-Ling, He, Jian-Xing, Liu, Liang, Leung, Elaine Lai-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271537/
https://www.ncbi.nlm.nih.gov/pubmed/24662070
http://dx.doi.org/10.3390/molecules19033508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271537/
https://www.ncbi.nlm.nih.gov/pubmed/24662070
http://dx.doi.org/10.3390/molecules19033508

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