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Dehydroabietic Acid Isolated from Commiphora opobalsamum Causes Endothelium-Dependent Relaxation of Pulmonary Artery via PI3K/Akt-eNOS Signaling Pathway

Commiphora opobalsamum is a Traditional Chinese Medicine used to treat traumatic injury, mainly by relaxing blood vessels. In this study, two diterpenes, dehydroabietic acid (DA) and sandaracopimaric acid (SA) were obtained from it by a bioassay-guided approach using isolated rat pulmonary artery ri...

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Detalles Bibliográficos
Autores principales: Gao, Wenyan, Dong, Xiaoyan, Xie, Nan, Zhou, Chunlan, Fan, Yuhua, Chen, Guoyou, Wang, Yanming, Wei, Taiming, Zhu, Daling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271577/
https://www.ncbi.nlm.nih.gov/pubmed/24959678
http://dx.doi.org/10.3390/molecules19068503