Phenoxyacetohydrazide Schiff Bases: β-Glucuronidase Inhibitors

Phenoxyacetohydrazide Schiff base analogs 1–28 have been synthesized and their in vitro β-glucouoronidase inhibition potential studied. Compounds 1 (IC(50) = 9.20 ± 0.32 µM), 5 (IC(50) = 9.47 ± 0.16 µM), 7 (IC(50) = 14.7 ± 0.19 µM), 8 (IC(50) = 15.4 ± 1.56 µM), 11 (IC(50) = 19.6 ± 0.62 µM), 12 (IC(5...

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Detalles Bibliográficos
Autores principales: Jamil, Waqas, Perveen, Shagufta, Shah, Syed Adnan Ali, Taha, Muhammad, Ismail, Nor Hadiani, Perveen, Shahnaz, Ambreen, Nida, Khan, Khalid M., Choudhary, Muhammad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271590/
https://www.ncbi.nlm.nih.gov/pubmed/24968334
http://dx.doi.org/10.3390/molecules19078788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271590/
https://www.ncbi.nlm.nih.gov/pubmed/24968334
http://dx.doi.org/10.3390/molecules19078788

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