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Cyclin-Dependent Kinase Inhibitors as Marketed Anticancer Drugs: Where Are We Now? A Short Survey

In the early 2000s, the anticancer drug imatinib (Glivec(®)) appeared on the market, exhibiting a new mode of action by selective kinase inhibition. Consequently, kinases became a validated therapeutic target, paving the way for further developments. Although these kinases have been thoroughly studi...

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Detalles Bibliográficos
Autores principales: Mariaule, Gaëlle, Belmont, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271685/
https://www.ncbi.nlm.nih.gov/pubmed/25215591
http://dx.doi.org/10.3390/molecules190914366