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RNA/aTNA Chimeras: RNAi Effects and Nucleases Resistance of Single and Double Stranded RNAs

The RNA interference pathway (RNAi) is a specific and powerful biological process, triggered by small non-coding RNA molecules and involved in gene expression regulation. In this work, we explored the possibility of increasing the biological stability of these RNA molecules by replacing their natura...

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Detalles Bibliográficos
Autores principales: Alagia, Adele, Terrazas, Montserrat, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271724/
https://www.ncbi.nlm.nih.gov/pubmed/25375332
http://dx.doi.org/10.3390/molecules191117872