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Semi-Automatic Synthesis, Antiproliferative Activity and DNA-Binding Properties of New Netropsin and bis-Netropsin Analogues

A general route for the semi-automatic synthesis of some new potential minor groove binders was established. Six four-numbered sub-libraries of new netropsin and bis-netropsin analogues have been synthesized using a Syncore Reactor. The structures of the all new substances prepared in this investiga...

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Detalles Bibliográficos
Autores principales: Szerszenowicz, Jakub, Drozdowska, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271738/
https://www.ncbi.nlm.nih.gov/pubmed/25090119
http://dx.doi.org/10.3390/molecules190811300